Steroid/Triterpenoid Functional Molecules based on “Click Chemistry”

Rational linkage of magnetic molecules using click chemistry.

CuAAC click reactions were used for the first time to assemble click-functionalized magnetic molecules into extended molecular arrangements in a deliberate manner.

Click Chemistry in Peptide-Based Drug Design

Click chemistry is an efficient and chemoselective synthetic method for coupling molecular fragments under mild reaction conditions. Since the advent in 2001 of methods to improve stereochemical conservation, the click chemistry approach has been broadly used to construct diverse chemotypes in both chemical and biological fields. In this review, we discuss the application of click chemistry in ...

Functional Polymer Gels by Click- and Supramolecular Chemistry

A versatile "click" chemistry precursor of functional polystyrene nanoparticles.

Functional nanoparticles (NPs) are becoming important building blocks in the emerging fi elds of nanomedicine, nanolithography and nanoelectronics, among others. [ 1 ] Several unexpected nanoscale effects have been discovered for these new materials in recent years. [ 2–4 ] Useful synthetic routes to single-molecule polymeric NPs in the 2–15 nm size range with well-defi ned arrangement of funct...

Click chemistry with DNAw